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DGKα-IN-2

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Catalog No. T79821Cas No. 2648556-92-5

DGKα-IN-2 (example 48), a potent DGKα inhibitor with an IC50 of 0.9 nM, significantly enhances the anti-tumor efficacy of anti-PD-1 therapy by amplifying T cell proliferation and function, making it a valuable agent for cancer and immunological research.

DGKα-IN-2

DGKα-IN-2

😃Good
Catalog No. T79821Cas No. 2648556-92-5
DGKα-IN-2 (example 48), a potent DGKα inhibitor with an IC50 of 0.9 nM, significantly enhances the anti-tumor efficacy of anti-PD-1 therapy by amplifying T cell proliferation and function, making it a valuable agent for cancer and immunological research.
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5 mgInquiry8-10 weeks
50 mgInquiry8-10 weeks
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Product Introduction

Bioactivity
Description
DGKα-IN-2 (example 48), a potent DGKα inhibitor with an IC50 of 0.9 nM, significantly enhances the anti-tumor efficacy of anti-PD-1 therapy by amplifying T cell proliferation and function, making it a valuable agent for cancer and immunological research.
Chemical Properties
Molecular Weight461.43
FormulaC23H22F3N3O4
Cas No.2648556-92-5
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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