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DS-003

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Catalog No. T202020Cas No. 676489-50-2
Alias DS003, DS 003, BMS-599793, BMS599793, BMS 599793

DS-003 is a small molecule Gp120 inhibitor. As an analog of BMS-378806, DS003 demonstrates enhanced inhibitory activity during prolonged exposure and when used in combination with fusion inhibitors. However, prior exposure to soluble CD4+ hinders DS003's binding to the viral envelope. Studies indicate that due to its targeting of the CD4+ binding site on Gp120, DS003 is a promising candidate for pre-exposure prophylactic therapy.

DS-003

DS-003

😃Good
Catalog No. T202020Alias DS003, DS 003, BMS-599793, BMS599793, BMS 599793Cas No. 676489-50-2
DS-003 is a small molecule Gp120 inhibitor. As an analog of BMS-378806, DS003 demonstrates enhanced inhibitory activity during prolonged exposure and when used in combination with fusion inhibitors. However, prior exposure to soluble CD4+ hinders DS003's binding to the viral envelope. Studies indicate that due to its targeting of the CD4+ binding site on Gp120, DS003 is a promising candidate for pre-exposure prophylactic therapy.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
DS-003 is a small molecule Gp120 inhibitor. As an analog of BMS-378806, DS003 demonstrates enhanced inhibitory activity during prolonged exposure and when used in combination with fusion inhibitors. However, prior exposure to soluble CD4+ hinders DS003's binding to the viral envelope. Studies indicate that due to its targeting of the CD4+ binding site on Gp120, DS003 is a promising candidate for pre-exposure prophylactic therapy.
AliasDS003, DS 003, BMS-599793, BMS599793, BMS 599793
Chemical Properties
Molecular Weight478.5
FormulaC27H22N6O3
Cas No.676489-50-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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