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DSPE-PEG(2000)-COOH is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE). This compound has been utilized to link transferrin receptors to the surfaces of liposomes encapsulating doxorubicin, facilitating the targeted delivery of doxorubicin both in vitro and in vivo. Additionally, nanomicelles incorporating DSPE-PEG(2000)-COOH and linked camphor, and encapsulating doxorubicin, have demonstrated efficacy in reducing tumor growth and metastasis in a murine orthotopic C6 glioma model.
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10 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | DSPE-PEG(2000)-COOH is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE). This compound has been utilized to link transferrin receptors to the surfaces of liposomes encapsulating doxorubicin, facilitating the targeted delivery of doxorubicin both in vitro and in vivo. Additionally, nanomicelles incorporating DSPE-PEG(2000)-COOH and linked camphor, and encapsulating doxorubicin, have demonstrated efficacy in reducing tumor growth and metastasis in a murine orthotopic C6 glioma model. |
Alias | 1,2-DSPE-PEG(2000)-COOH, 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine-Polyethylene Glycol-2000-COOH, 1,2-Distearoyl-sn-glycero-3-PE-Polyethylene Glycol-2000-COOH |
Formula | (C2H4O)nC48H91N2O13P |
Cas No. | 1445832-74-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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