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EBOV-IN-7

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Catalog No. T86334Cas No. 68207-16-9

EBOV-IN-7 (compound 26) acts as an inhibitor against the Ebola virus EBOV, displaying an IC 50 value of 2.04 μM against pEBOV (EBOV-GP pseudotyped virus). It also obstructs the EBOV-GPcl/NPC1 interaction and exhibits inhibitory effects on cancer cells. [8] [1]

EBOV-IN-7

EBOV-IN-7

😃Good
Catalog No. T86334Cas No. 68207-16-9
EBOV-IN-7 (compound 26) acts as an inhibitor against the Ebola virus EBOV, displaying an IC 50 value of 2.04 μM against pEBOV (EBOV-GP pseudotyped virus). It also obstructs the EBOV-GPcl/NPC1 interaction and exhibits inhibitory effects on cancer cells. [8] [1]
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
EBOV-IN-7 (compound 26) acts as an inhibitor against the Ebola virus EBOV, displaying an IC 50 value of 2.04 μM against pEBOV (EBOV-GP pseudotyped virus). It also obstructs the EBOV-GPcl/NPC1 interaction and exhibits inhibitory effects on cancer cells. [8] [1]
In vitro
EBOV-IN-7 (compound 26) exhibits a CC50 of 60 μM in HeLa cells, with low cytotoxicity in Vero cells (CC50 >100 μM) [1]. At a concentration of 50 μM, it significantly disrupts the interaction between EBOV-GPcl and NPC1, showing an IC50 of 2.04 μM against EBOV-GP-pseudotyped virus (pEBOV) [1]. For African swine fever virus (ASFV), the compound has an IC50 of 15.75 μM [1].
Chemical Properties
Molecular Weight406.89
FormulaC18H19ClN4O3S
Cas No.68207-16-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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