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EGFR/HER2-IN-14

Catalog No. T88221Cas No. 3034701-54-4

EGFR/HER2-IN-14 (Compd 46) serves as an inhibitor for drug-resistant mutant EGFR/HER2s. This compound is utilized in cancer research.

EGFR/HER2-IN-14

EGFR/HER2-IN-14

Catalog No. T88221Cas No. 3034701-54-4
EGFR/HER2-IN-14 (Compd 46) serves as an inhibitor for drug-resistant mutant EGFR/HER2s. This compound is utilized in cancer research.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
EGFR/HER2-IN-14 (Compd 46) serves as an inhibitor for drug-resistant mutant EGFR/HER2s. This compound is utilized in cancer research.
In vitro
EGFR/HER2-IN-14 exhibits an IC50 of less than 100 nM in Ba/F3 cells transfected with EGFR exon 20 insASV/insSVD and HER2 exon 20 insGSP/insYVMA mutations [1].
Chemical Properties
Molecular Weight575.62
FormulaC32H29N7O4
Cas No.3034701-54-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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