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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | EGFR-IN-97 (compound 6q), an EGFR inhibitor, demonstrates effectiveness in inhibiting Ba/F3-EGFR L858R/T790M/C797S and Ba/F3-EGFR Del19/T790M/C797S cells, exhibiting IC 50 values of 0.42 μM and 0.41 μM, respectively. Additionally, at a concentration of 0.8 μM, EGFR-IN-97 is capable of inducing apoptosis in NCI-H1975-EGFR L858R/T790M/C797S cells [1]. |
In vitro | EGFR-IN-97 (compound 6q) demonstrates remarkable efficacy against the mutant NSCLC cell line NCI-H1975-EGFR L858R/T790M/C797S, with an IC50 value of 0.82 μM, surpassing the performance of osimertinib (IC50 = 2.94 μM), JBJ-04-125-02 (IC50 = 3.66 μM), and the combination of JBJ-04-125-02 and osimertinib (IC50 = 1.25 μM) [1]. |
Molecular Weight | 624.73 |
Formula | C37H36N8O2 |
Cas No. | 3020681-05-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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