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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | endo-BCN-PEG4-NHS ester is a PEG-based linker used in PROTACs, facilitating the connection of two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands, connected by a linker: one targets an E3 ubiquitin ligase, and the other targets the desired protein. These compounds leverage the cellular ubiquitin-proteasome system to selectively degrade specific proteins [1]. |
Molecular Weight | 538.59 |
Formula | C26H38N2O10 |
Cas No. | 1807501-86-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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