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FALGPA TFA
Catalog No. T83722
Alias 2-Furanacryloyl-L-leucylglycyl-L-prolyl-L-alanine, 2-Furanacryloyl-Leu-Gly-Pro-Ala-OH
FALGPA, a colorimetric substrate for collagenase, exhibits selectivity over trypsin, thermolysin, and elastase. It uniquely interacts with collagenase, which binds to and cleaves the Leu-Gly (LG) peptide sequence, releasing the furanacryloyl group. This release is measurable through colorimetric detection between 324 and 345 nm, serving as an indicator of collagenase activity. Additionally, FALGPA facilitates the identification of inhibitors for C. histolyticum collagenase.
FALGPA TFA
Catalog No. T83722Alias 2-Furanacryloyl-L-leucylglycyl-L-prolyl-L-alanine, 2-Furanacryloyl-Leu-Gly-Pro-Ala-OH
FALGPA, a colorimetric substrate for collagenase, exhibits selectivity over trypsin, thermolysin, and elastase. It uniquely interacts with collagenase, which binds to and cleaves the Leu-Gly (LG) peptide sequence, releasing the furanacryloyl group. This release is measurable through colorimetric detection between 324 and 345 nm, serving as an indicator of collagenase activity. Additionally, FALGPA facilitates the identification of inhibitors for C. histolyticum collagenase.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $55 | Backorder | |
| 5 mg | $229 | Backorder | |
| 10 mg | $394 | Backorder | |
| 25 mg | $872 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | FALGPA, a colorimetric substrate for collagenase, exhibits selectivity over trypsin, thermolysin, and elastase. It uniquely interacts with collagenase, which binds to and cleaves the Leu-Gly (LG) peptide sequence, releasing the furanacryloyl group. This release is measurable through colorimetric detection between 324 and 345 nm, serving as an indicator of collagenase activity. Additionally, FALGPA facilitates the identification of inhibitors for C. histolyticum collagenase. |
| Alias | 2-Furanacryloyl-L-leucylglycyl-L-prolyl-L-alanine, 2-Furanacryloyl-Leu-Gly-Pro-Ala-OH |
| Molecular Weight | 476.52 |
| Formula | C23H32N4O7.XCF3COOH |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | PBS pH 7.2: Slightly soluble DMSO: 30 mg/ml Ethanol: 30 mg/ml DMF: 30 mg/ml |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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