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Ferroptosis-IN-11

Catalog No. T89034Cas No. 1266755-01-4

Ferroptosis-IN-11 (compound 43) is an inhibitor of ferroptosis, effectively suppressing Erastin-induced ferroptosis in HT-1080 human fibrosarcoma cells (EC50=36 nM). This compound is applicable in research related to cardiovascular diseases and neurodegeneration.

Ferroptosis-IN-11

Ferroptosis-IN-11

Catalog No. T89034Cas No. 1266755-01-4
Ferroptosis-IN-11 (compound 43) is an inhibitor of ferroptosis, effectively suppressing Erastin-induced ferroptosis in HT-1080 human fibrosarcoma cells (EC50=36 nM). This compound is applicable in research related to cardiovascular diseases and neurodegeneration.
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
Ferroptosis-IN-11 (compound 43) is an inhibitor of ferroptosis, effectively suppressing Erastin-induced ferroptosis in HT-1080 human fibrosarcoma cells (EC50=36 nM). This compound is applicable in research related to cardiovascular diseases and neurodegeneration.
Chemical Properties
Molecular Weight246.26
FormulaC14H12F2N2
Cas No.1266755-01-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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