Popular Searches
Cell Counting Kit-8 (CCK-8)Approved Drug LibraryMG-132
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact Us
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Signaling PathwaysOthersOthersGSK-5498A
TOPBioactivityChemical infoStorage&SolubilityCalculator

GSK-5498A

GSK-5498A
GSK-5498A is a selective blocker of CARC (IC50, 1 μM). It inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.
Catalog No. T11473Cas No. 1253186-49-0
Resource Download

GSK-5498A

Catalog No. T11473Cas No. 1253186-49-0
GSK-5498A is a selective blocker of CARC (IC50, 1 μM). It inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
Pack SizePriceAvailabilityQuantity
25 mg$9856-8 weeks
50 mg$1,2806-8 weeks
100 mg$1,9406-8 weeks
Bulk & Custom
Add to Cart
Questions
View More

Product Introduction

Bioactivity
Description
GSK-5498A is a selective blocker of CARC (IC50, 1 μM). It inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.
Chemical Properties
Molecular Weight399.29
FormulaC18H11F6N3O
Cas No.1253186-49-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (250.44 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5044 mL12.5222 mL25.0445 mL125.2223 mL
5 mM0.5009 mL2.5044 mL5.0089 mL25.0445 mL
10 mM0.2504 mL1.2522 mL2.5044 mL12.5222 mL
20 mM0.1252 mL0.6261 mL1.2522 mL6.2611 mL
50 mM0.0501 mL0.2504 mL0.5009 mL2.5044 mL
100 mM0.0250 mL0.1252 mL0.2504 mL1.2522 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

GSK5498AGSK-5498AGSK 5498A
Related Tags: buy GSK-5498A | purchase GSK-5498A | GSK-5498A cost | order GSK-5498A | GSK-5498A chemical structure | GSK-5498A formula | GSK-5498A molecular weight
TargetMol | Logo

Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.