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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $688 | 6-8 weeks | |
50 mg | $913 | 6-8 weeks | |
100 mg | $1,360 | 6-8 weeks |
Description | GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2 (pIC50: 7.81 for VEGFR2) with anti-angiogenic activity. |
In vitro | GW768505A free base acts as an inhibitor of both KDR and TIE2, demonstrating significant inhibition (71–88% inhibition at 100 nM) of tropomyosin-related kinases, including TRKA, TRKB, and TRKC. Furthermore, it exhibits inhibitory effects on the growth of cancer cells in the NCI-60 panel screening. |
Molecular Weight | 537.47 |
Formula | C27H19F4N5O3 |
Cas No. | 501693-25-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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