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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM. Additionally, it inhibits tau-oligomerization with an effective concentration half-maximum (EC50) of 2.71 μM as determined by a cellular tau fluorescence resonance energy transfer (FRET) assay [1]. |
In vitro | hAChE-IN-1 (Compound 24; 1-10 μM; 24 h) exhibits neuroprotective effects on SH-SY5Y cells transfected with WT tau [1]. |
Molecular Weight | 360.45 |
Formula | C22H24N4O |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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