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Haspin-IN-2

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Catalog No. T60394Cas No. 2768474-47-9

Haspin-IN-2 (compound 4) is a potent and selective inhibitor of haspin, with an IC50 of 50 nM, and also inhibits CLK1 and DYRK1A with IC50 values of 445 nM and 917 nM, respectively [1].

Haspin-IN-2

Haspin-IN-2

😃Good
Catalog No. T60394Cas No. 2768474-47-9
Haspin-IN-2 (compound 4) is a potent and selective inhibitor of haspin, with an IC50 of 50 nM, and also inhibits CLK1 and DYRK1A with IC50 values of 445 nM and 917 nM, respectively [1].
Pack SizePriceAvailabilityQuantity
25 mg$1,52010-14 weeks
50 mg$1,98010-14 weeks
100 mg$2,50010-14 weeks
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Product Introduction

Bioactivity
Description
Haspin-IN-2 (compound 4) is a potent and selective inhibitor of haspin, with an IC50 of 50 nM, and also inhibits CLK1 and DYRK1A with IC50 values of 445 nM and 917 nM, respectively [1].
Chemical Properties
Molecular Weight256.22
FormulaC12H8N4O3
Cas No.2768474-47-9
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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