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hCAI/II-IN-7

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Catalog No. T86546Cas No. 14204-32-1

hCAI/II-IN-7 (compound 1F) serves as a potent inhibitor of carbonic anhydrase (CA), exhibiting K i values of 23 nM and 44 nM for hCA-I and hCA-II, respectively, and a K i value of 20.57 µM for bovine CA [1].

hCAI/II-IN-7

hCAI/II-IN-7

😃Good
Catalog No. T86546Cas No. 14204-32-1
hCAI/II-IN-7 (compound 1F) serves as a potent inhibitor of carbonic anhydrase (CA), exhibiting K i values of 23 nM and 44 nM for hCA-I and hCA-II, respectively, and a K i value of 20.57 µM for bovine CA [1].
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
hCAI/II-IN-7 (compound 1F) serves as a potent inhibitor of carbonic anhydrase (CA), exhibiting K i values of 23 nM and 44 nM for hCA-I and hCA-II, respectively, and a K i value of 20.57 µM for bovine CA [1].
Targets&IC50
hCA I:23 nM (Ki), hCA II:44 nM (Ki), bovine CA:20.57 μM (Ki)
Chemical Properties
Molecular Weight334.19
FormulaC14H8BrNO2S
Cas No.14204-32-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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