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HH0043

Catalog No. T88773Cas No. 2922069-42-7

HH0043 (Compound 10f) is an orally active and potent inhibitor of SOS1, exhibiting an IC50 of 5.8 nM. It is applicable in cancer research.

HH0043

HH0043

Catalog No. T88773Cas No. 2922069-42-7
HH0043 (Compound 10f) is an orally active and potent inhibitor of SOS1, exhibiting an IC50 of 5.8 nM. It is applicable in cancer research.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
HH0043 (Compound 10f) is an orally active and potent inhibitor of SOS1, exhibiting an IC50 of 5.8 nM. It is applicable in cancer research.
Chemical Properties
Molecular Weight443.46
FormulaC23H24F3N5O
Cas No.2922069-42-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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