HKOCl-4m

HKOCl-4m is a rhodol-based fluorescent probe designed for the specific and deliberate targeting of mitochondria, enabling the monitoring of mitochondrial hypochlorous acid (HOCl).

Catalog No. T39433Cas No. 2031170-88-2

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HKOCl-4m

Catalog No. T39433Cas No. 2031170-88-2

HKOCl-4m is a rhodol-based fluorescent probe designed for the specific and deliberate targeting of mitochondria, enabling the monitoring of mitochondrial hypochlorous acid (HOCl).

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

Pack Size	Price	Availability	Quantity
5 mg	$747	Backorder
10 mg	$1,280	Backorder

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Product Introduction

Bioactivity

Description	HKOCl-4m is a rhodol-based fluorescent probe designed for the specific and deliberate targeting of mitochondria, enabling the monitoring of mitochondrial hypochlorous acid (HOCl).
In vitro	HKOCl-4m (5 μM; 30 min) demonstrates a significant increase in fluorescence intensity following HOCl addition. It has proven effective for detecting endogenous HOCl in RAW264.7 mouse macrophages and holds potential for monitoring mitochondrial HOCl formation in live cells[1].

Chemical Properties

Molecular Weight	1153.97
Formula	C₆₃H₆₁BrCl₂N₃O₇P
Cas No.	2031170-88-2

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Keywords

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