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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | HO-PEG11-OH, a PEG-based linker for PROTACs, connects two essential ligands necessary for forming PROTAC molecules, facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two ligands linked together: one targets an E3 ubiquitin ligase and the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs facilitate the selective degradation of target proteins[1]. |
Molecular Weight | 502.59 |
Formula | C22H46O12 |
Cas No. | 6809-70-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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