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HPK1-IN-8 is an allosteric, inactive, conformation-selective triazolopyrimidine ketone HPK1 inhibitor.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $1,255 | 1-2 weeks |
Description | HPK1-IN-8 is an allosteric, inactive, conformation-selective triazolopyrimidine ketone HPK1 inhibitor. |
In vitro | HPK1-IN-8 is an allosteric HPK1 inhibitor that attenuates kinase autophosphorylation by binding to a pocket consisting of residues inside and outside the kinase domain.[1] |
Molecular Weight | 412.44 |
Formula | C19H17FN6O2S |
Cas No. | 1214561-09-7 |
Smiles | O=C(NC1=NC=C(S1)CC=2C=CC=CC2F)CC=3C(=O)N4C(=NC3C)NN=C4C |
Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 8 mg/mL (19.4 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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