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HSD17B13-IN-27 (compound 30) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of less than 0.1 µM and approximately less than 1 µM for estradiol and Leukotriene B3, respectively, as substrates. This compound is crucial in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | HSD17B13-IN-27 (compound 30) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of less than 0.1 µM and approximately less than 1 µM for estradiol and Leukotriene B3, respectively, as substrates. This compound is crucial in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1]. |
Molecular Weight | 414.45 |
Formula | C21H19FN2O4S |
Cas No. | 2758802-31-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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