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HSD17B13-IN-74

Catalog No. T86665Cas No. 2912458-81-0

HSD17B13-IN-74 (Compound 760) serves as an inhibitor for hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting potent activity with an IC 50 of < 0.1 μM against estradiol. It has applications in research related to liver diseases or metabolic disorders [1].

HSD17B13-IN-74

HSD17B13-IN-74

Catalog No. T86665Cas No. 2912458-81-0
HSD17B13-IN-74 (Compound 760) serves as an inhibitor for hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting potent activity with an IC 50 of < 0.1 μM against estradiol. It has applications in research related to liver diseases or metabolic disorders [1].
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
HSD17B13-IN-74 (Compound 760) serves as an inhibitor for hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting potent activity with an IC 50 of < 0.1 μM against estradiol. It has applications in research related to liver diseases or metabolic disorders [1].
Chemical Properties
Molecular Weight636.73
FormulaC33H30F2N2O5S2
Cas No.2912458-81-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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