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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $30 | 5 days | |
10 mg | $41 | 5 days | |
25 mg | $64 | 5 days | |
50 mg | $92 | 5 days | |
100 mg | $133 | 5 days |
Description | Hydroxy-PEG4-O-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together: one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade these target proteins[1]. |
Molecular Weight | 352.42 |
Formula | C16H32O8 |
Cas No. | 1807530-05-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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