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IDH1 Inhibitor 9

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Catalog No. T88559Cas No. 3037967-71-5

IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.

IDH1 Inhibitor 9

IDH1 Inhibitor 9

😃Good
Catalog No. T88559Cas No. 3037967-71-5
IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.
Targets&IC50
R132H IDH1:124.4 nM, R132C IDH1:95.7 nM
In vivo
IDH1 Inhibitor 9 administered intraperitoneally (i.p.) at dosages of 20 and 40 mg/kg every two days over a period of eight days exhibited anti-tumor activity in an IDH1 mutant cancer model with no significant loss of body weight observed.
Chemical Properties
Molecular Weight446.54
FormulaC26H30N4O3
Cas No.3037967-71-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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