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IR-990

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Catalog No. T82052

IR-990, an activatable NIR-II fluorescent probe featuring an acceptor-π-acceptor (A-π-A) structure, enables real-time in vivo detection of hydrogen peroxide (H2O2). It serves as an effective diagnostic tool for drug-induced liver injury (DILI) [1].

IR-990

IR-990

😃Good
Catalog No. T82052
IR-990, an activatable NIR-II fluorescent probe featuring an acceptor-π-acceptor (A-π-A) structure, enables real-time in vivo detection of hydrogen peroxide (H2O2). It serves as an effective diagnostic tool for drug-induced liver injury (DILI) [1].
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Product Introduction

Bioactivity
Description
IR-990, an activatable NIR-II fluorescent probe featuring an acceptor-π-acceptor (A-π-A) structure, enables real-time in vivo detection of hydrogen peroxide (H2O2). It serves as an effective diagnostic tool for drug-induced liver injury (DILI) [1].
In vitro
Treatment with IR-990 (0-30 μM) demonstrates high cell viability [1].
In vivo
IR-990, administered via intravenous injection at a dose of 195.31 μg per mouse (single administration), serves as an effective agent for the real-time detection of H2O2 [1].
Chemical Properties
Storage & Solubility Information
Storagekeep away from direct sunlight | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy IR-990 | purchase IR-990 | IR-990 cost | order IR-990 | IR-990 in vivo | IR-990 in vitro
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