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JAK3-IN-13

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Catalog No. T63749

JAK3-IN-13 is a potent, selective, orally active JAK3 inhibitor with IC50 values of 4728 nM for NK1, 2039 nM for JNK2, 8 nM for JNK3, and 365 nM for Tyk2. JAK3-IN-13 also exhibits anti-tumor effects.

JAK3-IN-13

JAK3-IN-13

😃Good
Catalog No. T63749
JAK3-IN-13 is a potent, selective, orally active JAK3 inhibitor with IC50 values of 4728 nM for NK1, 2039 nM for JNK2, 8 nM for JNK3, and 365 nM for Tyk2. JAK3-IN-13 also exhibits anti-tumor effects.
Pack SizePriceAvailabilityQuantity
25 mg$1,52010-14 weeks
50 mg$1,98010-14 weeks
100 mg$2,50010-14 weeks
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Product Introduction

Bioactivity
Description
JAK3-IN-13 is a potent, selective, orally active JAK3 inhibitor with IC50 values of 4728 nM for NK1, 2039 nM for JNK2, 8 nM for JNK3, and 365 nM for Tyk2. JAK3-IN-13 also exhibits anti-tumor effects.
Chemical Properties
Molecular Weight533.02
FormulaC25H33ClN6O5
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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