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JANEX-1-M

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Catalog No. T202764Cas No. 406484-24-0
Alias JANEX1M, JANEX 1 M, 7-O-DEMETHYLJANEX-1

JANEX-1 is a JAK inhibitor metabolized by cytochrome P450 enzymes CYP1A1 and CYP1A2. The formation of JANEX-1-M follows Michaelis-Menten kinetics when in the presence of CYP1A1 and CYP1A2 expressed via baculovirus.

JANEX-1-M

JANEX-1-M

😃Good
Catalog No. T202764Alias JANEX1M, JANEX 1 M, 7-O-DEMETHYLJANEX-1Cas No. 406484-24-0
JANEX-1 is a JAK inhibitor metabolized by cytochrome P450 enzymes CYP1A1 and CYP1A2. The formation of JANEX-1-M follows Michaelis-Menten kinetics when in the presence of CYP1A1 and CYP1A2 expressed via baculovirus.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
JANEX-1 is a JAK inhibitor metabolized by cytochrome P450 enzymes CYP1A1 and CYP1A2. The formation of JANEX-1-M follows Michaelis-Menten kinetics when in the presence of CYP1A1 and CYP1A2 expressed via baculovirus.
AliasJANEX1M, JANEX 1 M, 7-O-DEMETHYLJANEX-1
Chemical Properties
Molecular Weight283.28
FormulaC15H13N3O3
Cas No.406484-24-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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