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JHU-083

Name: JHU-083
Brand: TargetMol
SKU: T15613
Price: 38 USD
Availability: InStock
Rating: 4.5 (1 reviews)

JHU-083 is a selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b+ cells. JHU-083 also experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals.

Catalog No. T15613Cas No. 1998725-11-3

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JHU-083

Catalog No. T15613Cas No. 1998725-11-3

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
25 mg	$1,520	2-4 weeks
50 mg	$1,980	2-4 weeks
100 mg	$2,500	2-4 weeks

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	312.37
Formula	C₁₄H₂₄N₄O₄
Cas No.	1998725-11-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (320.14 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2013 mL	16.0067 mL	32.0133 mL	160.0666 mL
5 mM	0.6403 mL	3.2013 mL	6.4027 mL	32.0133 mL
10 mM	0.3201 mL	1.6007 mL	3.2013 mL	16.0067 mL
20 mM	0.1601 mL	0.8003 mL	1.6007 mL	8.0033 mL
50 mM	0.0640 mL	0.3201 mL	0.6403 mL	3.2013 mL
100 mM	0.0320 mL	0.1601 mL	0.3201 mL	1.6007 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

JHU 083JHU-083JHU083