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JSH-0009 dimaleate

Catalog No. T88170Cas No. 2559759-04-3

JSH-0009 dimaleate (Compound 1), a potent CDK9 inhibitor, exhibits an IC50 of 0.928 nM. This compound demonstrably inhibits the growth of subcutaneous tumor (cute myelogenous leukemia MV4-11) in mice.

JSH-0009 dimaleate

JSH-0009 dimaleate

Catalog No. T88170Cas No. 2559759-04-3
JSH-0009 dimaleate (Compound 1), a potent CDK9 inhibitor, exhibits an IC50 of 0.928 nM. This compound demonstrably inhibits the growth of subcutaneous tumor (cute myelogenous leukemia MV4-11) in mice.
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
JSH-0009 dimaleate (Compound 1), a potent CDK9 inhibitor, exhibits an IC50 of 0.928 nM. This compound demonstrably inhibits the growth of subcutaneous tumor (cute myelogenous leukemia MV4-11) in mice.
Targets&IC50
CDK9/cyclinT1:0.928 nM, CDK1/cyclinB:5410 nM, CDK2/cyclinA:6850 nM, CDK3/cyclin E1:>10,000 nM, Cdk5/p25:6950 nM, CDK7/Cyclin H/MNAT1:3700 nM, CDK8/cyclin C:>10,000 nM
Chemical Properties
Molecular Weight751.25
FormulaC33H43ClN6O10S
Cas No.2559759-04-3
Storage & Solubility Information
Storagestore under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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