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KSI-6666 is an orally effective competitive antagonist of sphingosine 1-phosphate receptor 1 (S1PR1), with an IC50 value of 6.4 nM. It exhibits anti-inflammatory activity in models of autoimmune encephalomyelitis and T-cell transfer-induced colitis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | KSI-6666 is an orally effective competitive antagonist of sphingosine 1-phosphate receptor 1 (S1PR1), with an IC50 value of 6.4 nM. It exhibits anti-inflammatory activity in models of autoimmune encephalomyelitis and T-cell transfer-induced colitis. |
Targets&IC50 | S1PR1:6.4 nM |
Molecular Weight | 454.91 |
Formula | C23H26ClF3N2O2 |
Cas No. | 1807873-14-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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