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L 888607

Name: L 888607
Brand: TargetMol
SKU: T15828
Price: 518 USD
Availability: InStock
Rating: 4.5 (1 reviews)

Catalog No. T15828Cas No. 860033-06-3

L 888607 is an effective and selective CRTH2 agonist (Ki: 0.8 nM).

L 888607

Catalog No. T15828Cas No. 860033-06-3

L 888607 is an effective and selective CRTH2 agonist (Ki: 0.8 nM).

Pack Size	Price	Availability	Quantity
5 mg	$316	7-10 days
1 mL x 10 mM (in DMSO)	$313	7-10 days

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Product Introduction

Bioactivity

Description	L 888607 is an effective and selective CRTH2 agonist (Ki: 0.8 nM).
Targets&IC50	DP/DP1 receptor:2331 nM (ki), TP receptor:283 nM (ki), FPR:10018 nM (ki), CRTH2/DP2 receptor:0.8 nM (ki), EP4 receptor:4634 nM (ki), IP receptor:14434 nM (ki), EP3 III receptor:1260 nM (ki), EP2 receptor:8748 nM (ki)

Chemical Properties

Molecular Weight	375.84
Formula	C₁₉H₁₅ClFNO₂S
Cas No.	860033-06-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 150 mg/mL (399.11 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6607 mL	13.3035 mL	26.6071 mL	133.0353 mL
5 mM	0.5321 mL	2.6607 mL	5.3214 mL	26.6071 mL
10 mM	0.2661 mL	1.3304 mL	2.6607 mL	13.3035 mL
20 mM	0.1330 mL	0.6652 mL	1.3304 mL	6.6518 mL
50 mM	0.0532 mL	0.2661 mL	0.5321 mL	2.6607 mL
100 mM	0.0266 mL	0.1330 mL	0.2661 mL	1.3304 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

L888607L 888607L-888607