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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | Inquiry | 7-10 days | |
100 mg | Inquiry | 7-10 days |
Description | Lenalidomide-5-Br is a Lenalidomide derivative that functions as a ligand for cereblon (CRBN), thereby facilitating the recruitment of CRBN protein. It can be conjugated to the protein ligand through a linker to generate a PROTAC molecule. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Molecular Weight | 323.14 |
Formula | C13H11BrN2O3 |
Cas No. | 1010100-26-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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