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LSD1-IN-33

Catalog No. T88907

LSD1-IN-33 (7d) is an orally effective inhibitor of LSD1, exhibiting an IC50 of 4.51 nM. It alleviates the activation of NRCFs induced by Ang II and reduces pathological cardiac hypertrophy and heart failure due to TAC-induced cardiac remodeling.

LSD1-IN-33

LSD1-IN-33

Catalog No. T88907
LSD1-IN-33 (7d) is an orally effective inhibitor of LSD1, exhibiting an IC50 of 4.51 nM. It alleviates the activation of NRCFs induced by Ang II and reduces pathological cardiac hypertrophy and heart failure due to TAC-induced cardiac remodeling.
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Product Introduction

Bioactivity
Description
LSD1-IN-33 (7d) is an orally effective inhibitor of LSD1, exhibiting an IC50 of 4.51 nM. It alleviates the activation of NRCFs induced by Ang II and reduces pathological cardiac hypertrophy and heart failure due to TAC-induced cardiac remodeling.
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StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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