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LY2928057
🥰Excellent
Catalog No. T77383
Alias LY 2928057
LY2928057 is a humanized monoclonal antibody targeting the iron transporter SLC40A1, an iron-regulatory inhibitor used in cardiovascular disease research.
LY2928057
LY2928057
🥰Excellent
Catalog No. T77383Alias LY 2928057
LY2928057 is a humanized monoclonal antibody targeting the iron transporter SLC40A1, an iron-regulatory inhibitor used in cardiovascular disease research.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $447 | In Stock | |
| 5 mg | $1,400 | In Stock | |
| 10 mg | $2,240 | In Stock | |
| 25 mg | $4,210 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | LY2928057 is a humanized monoclonal antibody targeting the iron transporter SLC40A1, an iron-regulatory inhibitor used in cardiovascular disease research. |
| In vitro | LY2928057 is a monoclonal antibody targeting iron transporters. LY2928057 binds to ferritransporter and blocks its interaction with ferrimodulin, resulting in iron efflux, resulting in elevated serum iron and transferrin saturation levels and increased ferrimodulin in monkeys and humans. [1] |
| In vivo | The administration of LY2928057 (10-30 mg/kg) resulted in a dose-dependent increase in serum ferritin in cynomophores.[2] |
| Alias | LY 2928057 |
| Molecular Weight | 145.5 |
| Smiles | #N/A |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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