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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | m-PEG-thiol (MW 5000) is a PEG-based linker used in PROTACs, facilitating the conjugation of essential ligands necessary for PROTAC molecule formation, and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked by a connector: one ligand binds to an E3 ubiquitin ligase, and the other targets the specific protein. They leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins[1]. |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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