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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | m-PEG5-phosphonic acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands necessary for PROTAC molecule formation. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other binds the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 316.29 |
Formula | C11H25O8P |
Cas No. | 1807512-39-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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