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m-PEG6-2-methylacrylate is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $34 | 5 days | |
10 mg | $47 | 5 days | |
25 mg | $76 | 5 days |
Description | m-PEG6-2-methylacrylate is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands joined by a linker: one targets an E3 ubiquitin ligase and the other binds to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 364.43 |
Formula | C17H32O8 |
Cas No. | 90784-86-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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