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Description | m-PEG5-NHS ester is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Molecular Weight | 377.39 |
Formula | C16H27NO9 |
Cas No. | 874208-94-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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