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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | m-PEG5-nitrile is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the selective degradation of proteins by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked by a connector: one ligand binds to an E3 ubiquitin ligase, while the other targets the protein of interest. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Molecular Weight | 261.31 |
Formula | C12H23NO5 |
Cas No. | 81836-41-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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