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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | m-PEG8-DBCO, a PEG-based linker for PROTACs, connects two essential ligands necessary for PROTAC molecule formation. This linker facilitates selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked by a connector: one ligand targets an E3 ubiquitin ligase, while the other targets the protein of interest. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 670.79 |
Formula | C36H50N2O10 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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