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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Mal-PEG1-bromide, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting two different ligands with a linker: one ligand targets an E3 ubiquitin ligase, and the other binds to the target protein [1]. |
Molecular Weight | 248.07 |
Formula | C8H10BrNO3 |
Cas No. | 1823885-81-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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