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MEK/PI3K-IN-2

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Catalog No. T74361Cas No. 2281803-33-4

MEK/PI3K-IN-2 (compound 6s), a potent inhibitor of both MEK and PI3K, demonstrates IC50 values of 352 nM (MEK1), 107 nM (PI3Kα), and 137 nM (PI3Kδ), effectively reducing pAKT and pERK1/2 levels and exhibiting anti-proliferative activity against various tumor cell lines [1].

MEK/PI3K-IN-2

MEK/PI3K-IN-2

😃Good
Catalog No. T74361Cas No. 2281803-33-4
MEK/PI3K-IN-2 (compound 6s), a potent inhibitor of both MEK and PI3K, demonstrates IC50 values of 352 nM (MEK1), 107 nM (PI3Kα), and 137 nM (PI3Kδ), effectively reducing pAKT and pERK1/2 levels and exhibiting anti-proliferative activity against various tumor cell lines [1].
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Product Introduction

Bioactivity
Description
MEK/PI3K-IN-2 (compound 6s), a potent inhibitor of both MEK and PI3K, demonstrates IC50 values of 352 nM (MEK1), 107 nM (PI3Kα), and 137 nM (PI3Kδ), effectively reducing pAKT and pERK1/2 levels and exhibiting anti-proliferative activity against various tumor cell lines [1].
Chemical Properties
Molecular Weight957.68
FormulaC38H41F5IN9O7
Cas No.2281803-33-4
Storage & Solubility Information
StorageShipping with blue ice.

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