Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $78 | 35 days | |
10 mg | $143 | 35 days | |
25 mg | $273 | 35 days | |
50 mg | $297 | 35 days |
Description | Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm. |
Molecular Weight | 590.63 |
Formula | C27H38N6O9 |
Cas No. | 70967-90-7 |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | Ethanol: 25 mg/mL DMSO: 20 mg/mL PBS (pH 7.2): 25 mg/mL DMF: 2 mg/mL |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.