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MJN228

Name: MJN228
Brand: TargetMol
SKU: T28050
Price: 89 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T28050Cas No. 459168-97-9

Alias MJN-228, MJN 228

MJN228 is a lipid-binding protein nucleobindin-1 (NUCB1) inhibitor that blocks the AEA-DA probe labeling of endogenous NUCB1 in Neuro2a cells and can be used for the study of metabolic disorders.

MJN228

🥰Excellent

Catalog No. T28050Alias MJN-228, MJN 228Cas No. 459168-97-9

MJN228 is a lipid-binding protein nucleobindin-1 (NUCB1) inhibitor that blocks the AEA-DA probe labeling of endogenous NUCB1 in Neuro2a cells and can be used for the study of metabolic disorders.

Pack Size	Price	Availability
1 mg	$89	In Stock
5 mg	$219	In Stock
10 mg	$326	In Stock
25 mg	$546	In Stock
50 mg	$778	In Stock

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COA

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	MJN228 is a lipid-binding protein nucleobindin-1 (NUCB1) inhibitor that blocks the AEA-DA probe labeling of endogenous NUCB1 in Neuro2a cells and can be used for the study of metabolic disorders.
In vitro	25 μM MJN228 significantly reduced lipid probe labeling of NUCB1 in Neuro2a cells. [1] MJN228 interfered with multiple intracellular lipid metabolic pathways. [1]
Alias	MJN-228, MJN 228

Chemical Properties

Molecular Weight	364.4
Formula	C₂₀H₂₀N₄O₃
Cas No.	459168-97-9
Smiles	O=C(N1CCN(CC1)C)C2=C(C3=CC=CC=C3)C4=C(C=CC([N+]([O-])=O)=C4)N2
Relative Density.	1.324 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 20 mg/mL (54.88 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7442 mL	13.7212 mL	27.4424 mL	137.2119 mL
5 mM	0.5488 mL	2.7442 mL	5.4885 mL	27.4424 mL
10 mM	0.2744 mL	1.3721 mL	2.7442 mL	13.7212 mL
20 mM	0.1372 mL	0.6861 mL	1.3721 mL	6.8606 mL
50 mM	0.0549 mL	0.2744 mL	0.5488 mL	2.7442 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MJN228