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Pack Size | Price | Availability | Quantity |
---|---|---|---|
250 mg | $173 | 35 days |
Description | MOMBA is a selective orthosteric agonist specifically targeting engineered human free fatty acid 2 (hFFA2) receptors, particularly those modified as designer receptors activated by designer drugs (DREADD). It demonstrates selective inactivity towards wild-type hFFA2, hFFA3, and mouse FFA2 receptors. It efficiently inhibits forskolin-induced cAMP levels in cells equipped with the hFFA2-DREADD receptor, exhibiting enhanced potency and comparable efficacy to Sorbic acid. In transgenic mice containing the hFFA2-DREADD gene, MOMBA administration notably slows gut transit and facilitates a concentration-dependent enhancement of GLP-1 secretion from colonic crypts, all while being orally bioavailable. |
Molecular Weight | 166.17 |
Formula | C9H10O3 |
Cas No. | 6880-04-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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