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MONIRO-1

Catalog No. T62876Cas No. 1909225-94-0

MONIRO-1 is a T- and N-type calcium channel blocker that acts on hCav2.2 (IC50: 34 μM), hCav3.1 (IC50: 3.3 μM), hCav3.2 (IC50: 1.7 μM) and hCav3.3 (IC50: 7.2 μM).

MONIRO-1

MONIRO-1

Catalog No. T62876Cas No. 1909225-94-0
MONIRO-1 is a T- and N-type calcium channel blocker that acts on hCav2.2 (IC50: 34 μM), hCav3.1 (IC50: 3.3 μM), hCav3.2 (IC50: 1.7 μM) and hCav3.3 (IC50: 7.2 μM).
Pack SizePriceAvailabilityQuantity
25 mg$1,5208-10 weeks
50 mg$1,9808-10 weeks
100 mg$2,5008-10 weeks
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Product Introduction

Bioactivity
Description
MONIRO-1 is a T- and N-type calcium channel blocker that acts on hCav2.2 (IC50: 34 μM), hCav3.1 (IC50: 3.3 μM), hCav3.2 (IC50: 1.7 μM) and hCav3.3 (IC50: 7.2 μM).
Chemical Properties
Molecular Weight458.92
FormulaC23H24ClFN4O3
Cas No.1909225-94-0
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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