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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $35 | 5 days | |
5 mg | $53 | 5 days |
Description | 'N,N'-DME-N-PEG2-Boc is a PEG-based linker used in the formation of PROTAC molecules by connecting two essential ligands. This linker facilitates selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 304.43 |
Formula | C15H32N2O4 |
Cas No. | 2279944-69-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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