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N-butyl Lithocholic acid is a derivative of the secondary bile acid lithocholic acid. Lipid nanoparticles containing N-butyl Lithocholic acid and encapsulating mRNA vaccines that express hemagglutinin show reduced cardiotoxicity, splenic, and hepatic toxicity in mice compared to lipid nanoparticles that contain cholesterol.
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50 mg | Inquiry | Backorder |
Description | N-butyl Lithocholic acid is a derivative of the secondary bile acid lithocholic acid. Lipid nanoparticles containing N-butyl Lithocholic acid and encapsulating mRNA vaccines that express hemagglutinin show reduced cardiotoxicity, splenic, and hepatic toxicity in mice compared to lipid nanoparticles that contain cholesterol. |
Alias | N-butyl Lithocholate, N-butyl LCA |
Molecular Weight | 432.68 |
Formula | C28H48O3 |
Cas No. | 135013-42-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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