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Ndpih
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Catalog No. TN8363Cas No. 1360168-37-1
NDPIH, derived from Hericium erinaceus (monkey head mushroom), exhibits significant neurotrophic activity. It enhances extensive axonal growth and synaptic branching in cultured hippocampal neurons under serum-free conditions. Although pharmacological inhibition of actin receptor kinase B (TrkB) partially blocks the activity induced by NDPIH, the compound can independently activate the ERK1/2 signaling pathway, bypassing TrkB.
Ndpih
😃Good
Catalog No. TN8363Cas No. 1360168-37-1
NDPIH, derived from Hericium erinaceus (monkey head mushroom), exhibits significant neurotrophic activity. It enhances extensive axonal growth and synaptic branching in cultured hippocampal neurons under serum-free conditions. Although pharmacological inhibition of actin receptor kinase B (TrkB) partially blocks the activity induced by NDPIH, the compound can independently activate the ERK1/2 signaling pathway, bypassing TrkB.
| Pack Size | Price | Availability | Quantity |
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| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | NDPIH, derived from Hericium erinaceus (monkey head mushroom), exhibits significant neurotrophic activity. It enhances extensive axonal growth and synaptic branching in cultured hippocampal neurons under serum-free conditions. Although pharmacological inhibition of actin receptor kinase B (TrkB) partially blocks the activity induced by NDPIH, the compound can independently activate the ERK1/2 signaling pathway, bypassing TrkB. |
| Molecular Weight | 315.41 |
| Formula | C19H25NO3 |
| Cas No. | 1360168-37-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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