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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | NDT-19795 is a potent NLRP3 inflammasome inhibitor with an IC 50 value of 66 nM using the PBMC method and 4.7 μM using the WB method. It is a carboxylic acid-active compound that can be derived from NT-0796 within cells, and is applicable for neurological disease research [1]. |
In vivo | Administered intravenously as a single dose of 3 mg/kg, NDT-19795 exhibits a brain-to-blood ratio of 0.07 in C57BL/6 mice, indicating low permeability across the blood-brain barrier [1]. |
Molecular Weight | 367.4 |
Formula | C20H21N3O4 |
Cas No. | 2272917-12-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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