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Neuraminidase-IN-21

Catalog No. T88947

Neuraminidase-IN-21 (Compound 6d) is an inhibitor of the influenza H1N1 virus neuraminidase, boasting an IC50 value of 0.30 µM against the neuraminidase enzyme and 30.01 µM against the H1N1 virus strain. It forms three hydrogen bonds with the neuraminidase residues Arg292, Arg371, and Tyr406.

Neuraminidase-IN-21

Neuraminidase-IN-21

Catalog No. T88947
Neuraminidase-IN-21 (Compound 6d) is an inhibitor of the influenza H1N1 virus neuraminidase, boasting an IC50 value of 0.30 µM against the neuraminidase enzyme and 30.01 µM against the H1N1 virus strain. It forms three hydrogen bonds with the neuraminidase residues Arg292, Arg371, and Tyr406.
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Product Introduction

Bioactivity
Description
Neuraminidase-IN-21 (Compound 6d) is an inhibitor of the influenza H1N1 virus neuraminidase, boasting an IC50 value of 0.30 µM against the neuraminidase enzyme and 30.01 µM against the H1N1 virus strain. It forms three hydrogen bonds with the neuraminidase residues Arg292, Arg371, and Tyr406.
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Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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