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NLRP3-IN-61 (Compound 1) is an inhibitor of NLRP3. It suppresses pyroptosis in THP-1 cells with an IC50 of 12.6 nM and inhibits IL-β release with an IC50 of 25.3 nM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | NLRP3-IN-61 (Compound 1) is an inhibitor of NLRP3. It suppresses pyroptosis in THP-1 cells with an IC50 of 12.6 nM and inhibits IL-β release with an IC50 of 25.3 nM. |
Molecular Weight | 363.41 |
Formula | C21H21N3O3 |
Cas No. | 3060585-94-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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